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KMID : 0359719970150030624
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Journal of the Korean Neurological Association
1997 Volume.15 No. 3 p.624 ~ p.633
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Tc-99m HM-PAO SPECT in Migraine between Attacks
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성상민
김상화/문인수/김대성/정대수/박규현 김용기
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Abstract
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echnetium-99m hexamethylene-propyleneamine oxime (Tc-99m HM-PAO) SPECT brain imaging was performed in patients with migraine without aura(n=32) and migraine with aura(n=29) durig the headache-free period. A regional alteration of tracer uptake
into
brain was observed in 21 cases of migraine without aura (65.6%, 18 cases : reduction, 3 cases : increment) and in 20 cases of migraine with aura(69%, all cases : reduction, including 10 cases : hemiplegic or hemisensory aura, 10 cases : only
visual
aura). In most cases(73.%) of migraine with aura, the areas of decreased tracer uptake was exclusively concordant with the areas of unilateral aura. The concordance between the area of associated focal neurological symptoms(aura) and the area of
regional hypoperfusion was observed in 9 cases(69.2%) of hemiplegic or hemisensory aura(13 cases). The concordance between the site of headache and the areas of regional hypoperfusion of hyperperfusion was observed in 30 cases(49.2%) of migraine
with or
without aura. Therefore an impaired regional cerebral vascular autoregulation may exist even during headache-free intervals in patients suffering migraine with or without aura. It may be concluded that migraine attacks occur in association with
exacerbation of preexisting change of cerebral autoregulation.
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KEYWORD
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